Collagen Stimulation Filler

Collagen stimulation filler is a next generation collagen-stimulating dermal filler. Its main ingredient is PDLLA (Poly-D-L-lactic Acid), which is an FDA-approved, biocompatible, biodegradable, and biostimulator substance. Collagen stimulation filler helps to naturally stimulate the production of collagen. Unlike traditional fillers, collagen stimulation filler works by restoring natural volume to the contours of your face, resulting in a rejuvenated and younger appearance.

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Reviewed by Dr Zubin Firdos Medora, Medical Director
Last reviewed 13 October 2026

Illustration for Collagen Stimulation Filler

What are the benefits?

Safe: Collagen stimulation filler is made of PDLLA (poly-D-L-lactic Acid) which is US FDA approved.
Customizable: Doctor can adjust its concentration for injection to different treatment areas to help achieve your desired outcome.
No Migration: Collagen stimulation filler stays in the injected treatment area and does not move to other parts of your face.
Lasting Results: After treatment, collagen stimulation filler continues to stimulate collagen production; allowing the results to last up to 2 years.

Which areas of the face can collagen stimulation filler treat?

Collagen stimulation filler can be safely injected in the following areas:

Temples
Forehead
Undereye
Cheeks
Nasolabial folds
Marionette lines
Chin, Jawline
Neck

How many treatments do I need?

Recommended a course of 2-3 injection sessions spaced 4 weeks apart to see clinically appreciable results. When can I start to see results and how long do they last?

Results can be noticed almost immediately after the treatment.

However, after the first week, there might be a slight reduction in the initial outcomes. This is a normal occurrence caused by the absorption and excretion of the solvent, primarily water, from the injected areas.

You will see more noticeable results over the next 1 to 2 months as new collagen generates gradually.

Once desired results have been achieved, collagen stimulation filler can last up to 2 years.

How soon can I return to normal activities?

There is minimal downtime, you can actually resume your usual lifestyle as soon as your treatment is over.

Are there any side effects?

Fillers used nowadays are generally safe and seldom produce severe side effects. The most common side effects are injection-related, such as redness, pain, itching, swelling or bruising. These post-treatment reactions are usually mild and subside after a few days.