PCL Filler

PCL filler is a collagen stimulating filler that provides immediate and long lasting results. It is used to reverse facial aging and improve loose skin by restoring collagen and volume that has been lost due to the aging process. It is used to lift and sculpt areas of the face including the forehead, temples, cheeks, nasolabial fold and chin. In recent years it has been gaining popularity especially in the Chinese market, where it is known as 少女针 “young woman’s injection”. Unlike most other dermal fillers which contain hyaluronic acid and last for about 9 to 18 months, PCL filler contains Polycaprolactone (PCL)- a potent collagen stimulator that promotes new collagen formation in the area of treatment, with long lasting results of over 24 months. The ideal candidate for PCL filler is someone who has had hyaluronic acid based dermal fillers before, liked the result and is seeking a treatment that is more long lasting.

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Reviewed by Dr Zubin Firdos Medora, Medical Director
Last reviewed 13 October 2026

How does PCL filler work?

PCL filler is a dermal filler that contains 30% polycaprolactone (PCL) microspheres suspended in a 70% Carboxymethylcellulose (CMC) gel carrier. The CMC gel provides an immediate but short-lived (8-12 weeks) volume restoration of the treated area, while the PCL microspheres are absorbed gradually over 1 to 4 years, stimulating collagen production in the skin to provide a natural and long-lasting (1-4 years) improvement in facial volume and skin quality.

The PCL microspheres in PCL filler have a unique property, they stimulate the production of collagen, a protein that aids in the preservation of skin structure and elasticity. Over time, as the PCL microspheres gradually break down, they trigger the body’s natural collagen production process. This collagen production helps to rejuvenate and restore the skin from within.

The collagen that is produced as a result of PCL filler treatment replaces the gel carrier, providing long-lasting improvements to the treated area. The combination of immediate volumisation and ongoing collagen stimulation creates a natural and rejuvenated appearance.

Who is suitable for PCL Filler?

PCL Filler is suitable for clients who wish to look like their younger selves by reversing age related facial volume loss and skin laxity. Contraindications include major medical and dermatological disease, presence of permanent facial implant, active skin infection and pregnancy.

Illustration of a doctor and a patient talking at a consultation table

Why is PCL Filler the Key to Facial Rejuvenation

PCL filler has the unique ability to naturally regenerate volume in the skin that helps restore a youthful appearance.
The newly produced collagen helps to rejuvenate and restore the skin from within, leading to long-lasting results.
PCL filler combines immediate volumization with the ongoing stimulation of collagen production. By addressing both volume loss and collagen depletion, PCL filler offers comprehensive rejuvenation benefits.
PCL filler has gained approval from regulatory bodies such as the MHRA in the UK and the HSA in Singapore. This ensures that it meets stringent safety and efficacy standards, providing patients with confidence in its use for facial rejuvenation.